Spasmolytics, also known as "centrally acting" muscle relaxants, are used to alleviate musculoskeletal pain and spasms and to reduce spasticity in a variety of neurological conditions.While both neuromuscular blockers and spasmolytics are often grouped together as muscle relaxants, Thee earliest known use of muscle relaxant drugs was by natives of the Amazon Basin in South America who used poison-tipped arrows that produced death by skeletal muscle paralysis.The cookies contain no personally identifiable information and have no effect once you leave the Medscape site.
It may be used to alleviate symptoms such as muscle spasms, pain, and hyperreflexia.
The term "muscle relaxant" is used to refer to two major therapeutic groups: neuromuscular blockers and spasmolytics.
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But there may be benefit to taking both, especially at night, where a muscle relaxant added to acetaminophen or an NSAID works better than either alone. How well do they work and what are their side effects ?
This review investigates the efficacy, side effects, and safety of three commonly prescribed skeletal muscle relaxants metaxalone (Skelaxin), cyclobenzaprine (Flexeril), and carisoprodol (Soma).
Improving Range of Motion: A Goal of Muscle Relaxant Treatment Muscle relaxants are often prescribed in the treatment of acute low back pain in an attempt to improve the initial limitations in range of motion from muscle spasm and to interrupt the pain-spasm-pain cycle.
Limiting muscle spasm and improving range of motion will prepare you for therapeutic exercise (which should, in the long run, provide you with more lasting pain relief).
Tolperisone, an approved product that has regulatory approval and is commercialized in many countries outside the United States, has demonstrated improvement in the treatment of skeletal muscle disorders without sedation.